Duphalac: What It Is, How It Works, and When to Use It

Duphalac is the brand name for lactulose, a sugar‑based medicine that pulls water into the colon. The extra fluid softens stool and makes it easier to pass, which is why doctors prescribe it for constipation. It also helps lower ammonia levels in people with liver disease, so it’s a go‑to for hepatic encephalopathy.

Because it’s not an opioid or stimulant laxative, Duphalac works in a gentle, predictable way. Most people notice relief within a day or two, but the exact timing depends on the dose and how your gut reacts. If you’re new to it, start low, see how you feel, and adjust as needed.

Typical Dosage for Adults

For constipation, the usual adult dose is 15‑30 mL (about 10‑20 g) once a day, taken with water or juice. Some doctors split the dose into two smaller servings to avoid bloating. When treating hepatic encephalopathy, the goal is to reduce blood ammonia, so the dose may be higher—often 30‑45 mL (20‑30 g) three times a day, adjusted based on lab results.

Kids and seniors often need a reduced amount. Pediatric dosing starts around 0.5 mL per kilogram of body weight, given two to three times daily. Always follow your doctor’s exact instructions; don’t guess the dose based on bottle size alone.

Side Effects and Safety Tips

The most common side effect is gas. Lactulose ferments in the gut, creating hydrogen and carbon dioxide, which can cause flatulence or a mild stomach rumble. Diarrhea is another sign you might be taking too much—if stools become watery, cut back a dose and talk to your pharmacist.

Rarely, people develop severe cramps or electrolyte imbalances, especially if they’re on high doses for liver disease. Stay hydrated, and if you feel dizzy, light‑headed, or notice muscle twitching, reach out to your healthcare provider.

Duphalac is safe for most patients, but there are a few red flags:

• If you have a blockage in your intestines, lactulose can worsen it.
• People with diabetes should monitor blood sugar, as lactulose contains a small amount of sugar.
• Pregnant or breastfeeding mothers should confirm with their doctor before starting.

Never mix Duphalac with other laxatives unless a doctor says it’s okay. Combining multiple agents can cause sudden, heavy diarrhea and dehydration.

When you first start, keep a simple log: note the dose, time of day, and how your stool looks. This record helps your doctor fine‑tune the treatment without trial‑and‑error.

If you miss a dose, take it as soon as you remember—unless it’s close to the next scheduled dose. In that case, skip the missed one and continue your regular schedule. Don’t double up; that only raises the chance of cramps.

Finally, store Duphalac at room temperature, away from direct sunlight, and keep the bottle tightly closed. The medicine stays stable for years, but contaminated containers can affect taste and effectiveness.

With the right dose and a few practical habits, Duphalac can turn a stubborn constipation problem into a smooth, regular routine, and it can keep ammonia levels in check for those managing liver disease. Keep these tips handy, and you’ll get the most out of your treatment without unnecessary side effects.